Familial Mediterranean Fever
Familial Mediterranean Fever
A genetic condition causing episodes of severe inflammation, primarily affecting joints and abdomen. Understanding the triggers and managing symptoms is key.
Read our guide to: Familial Mediterranean Fever
Familial Mediterranean Fever
A genetic condition causing episodes of severe inflammation, primarily affecting joints and abdomen. Understanding the triggers and managing symptoms is key.
Treatment and Care Options
Treatment for FMF focuses on preventing severe flare-ups (fevers and abdominal pain) through medication and managing inflammation. High doses of colchicine are often prescribed as the primary treatment to reduce inflammation and prevent life-threatening complications.
Supportive care at home includes identifying and avoiding known triggers, such as extreme stress or certain dietary habits, and maintaining a healthy lifestyle. Always follow the dosing schedule prescribed by your rheumatologist.
What Causes this Condition?
Familial Mediterranean Fever (FMF) is an autoimmune, genetic condition. It is not caused by infection, but rather by a defect in a gene (MEFV) that affects how the body controls inflammation.
- A genetic predisposition (MEFV gene mutation) that leads to excessive inflammation.
- The body's inflammatory process overreacts to minor stimuli, causing episodes of fever and pain.