Zollinger-Ellison Syndrome
Zollinger-Ellison Syndrome
Treatment and Care Options
Treating Zollinger-Ellison Syndrome focuses on managing the excess stomach acid and protecting the digestive tract. Treatment usually requires close monitoring by a gastroenterologist.
Medication Management
- Proton Pump Inhibitors (PPIs): These powerful medications reduce the amount of acid your stomach produces. They are often the first line of defense.
- H2 Blockers: These medications also reduce acid production, though often less powerfully than PPIs.
- Antibiotics: Sometimes, antibiotics are used to help heal ulcers in the gut caused by excess acid.
Managing the Underlying Tumor
If the cause is a gastrinoma, treatment may involve removing the tumor (surgery). If surgery is not feasible, other treatments may be used to lower the gastrin levels.
Dietary and Supportive Care
While diet does not cure ZES, avoiding known irritants can help manage symptoms. These include spicy foods, caffeine, and alcohol, especially when symptoms are active. Eating smaller, more frequent meals can also help reduce stomach acid buildup.
What Causes this Condition?
Zollinger-Ellison Syndrome (ZES) is primarily caused by an overproduction of stomach acid. This excess acid is usually due to a specific type of tumor, often called a gastrin-secreting tumor (gastrinoma).
- Gastrinoma: This is the most common cause. The tumor, usually found in the stomach or pancreas, releases excessive amounts of the hormone gastrin.
- Excess Gastrin: High levels of gastrin signal the stomach lining to produce too much acid, leading to chronic over-secretion.