Lasix

Pregnancy

Furosemide is classified as a Category C medication. There are no adequate and well-controlled studies in pregnant women; however, animal studies have shown adverse effects on the fetus. Patients are advised to use furosemide during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation

Furosemide is excreted in human milk. The effects on a breastfed infant are not well studied, and there is a potential for adverse effects on milk production. Patients are advised to weigh the importance of the drug to the mother against the potential risk to the infant.

Pediatric Use

The safety and efficacy of furosemide in pediatric patients have been established in neonates, infants, and children. However, dosing should be carefully considered, and the use of furosemide in this population should be guided by clinical judgment.

Geriatric Use

Elderly patients may exhibit increased sensitivity to furosemide. Dose adjustments may be necessary, and caution is advised due to the potential for renal impairment and electrolyte imbalances in this population.

Renal Impairment

Dosing of furosemide may need to be adjusted in patients with renal impairment. The label advises that the drug should be used with caution in patients with reduced renal function, and monitoring of renal function is recommended.

Hepatic Impairment

In patients with hepatic impairment, furosemide should be used with caution. The label does not provide specific dosing adjustments based on Child-Pugh class, but monitoring for efficacy and safety is recommended.